BB-22
Product Specifications
UNSPSC Description
BB-22 is a third generation SPICE/K2 cannabinoid wih dopamine (DA) stimulant properties. BB-22 shows affinity to CB1 receptors with a Ki value of 0.11 nM and an EC50 value of 2.9 nM. BB-22 also stimulates CB1-induced [35S]GTPγS binding[1].
Target Antigen
Cannabinoid Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bb-22.html
Smiles
O=C(C1=CN(CC2CCCCC2)C3=C1C=CC=C3)OC4=C5N=CC=CC5=CC=C4
Molecular Weight
384.47
References & Citations
[1]De Luca MA, et al. Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135. Neuropharmacology. 2016 Jun;105:630-638.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12244/BB-22-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12244/
Clinical Information
No Development Reported
CAS Number
1400742-42-8
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