Lathosterol

Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005) -induced liver injury[1][2].

Product Specifications

CAS Number

[80-99-9]

Product Name Alternative

BHI1

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Lactate Dehydrogenase; SOD

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Lathosterol.html

Purity

99.38

Solubility

DMSO : 2 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)

Smiles

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C27H46O

Molecular Weight

386.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29 (9) :1149-55.|[2]Ullah H, et al. Lophenol and lathosterol from resin of Commiphora kua possess hepatoprotective effects in vivo. J Ethnopharmacol. 2020 Apr 24;252:112558.