MK-28
Product Specifications
UNSPSC Description
MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1].
Target Antigen
PERK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk-28.html
Smiles
OC1=CC=C(C=C1O)/C=N/N(C2=NC(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=N2)C
Molecular Weight
396.44
References & Citations
[1]Javier Ganz, et al. A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models. Sci Rep. 2020 Apr 23;10(1):6875.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137207/MK-28-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137207/MK-28-SDS-MedChemExpress.pdf
CAS Number
864388-65-8
Available Sizes
Curated Selection
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