Protirelin

Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

Product Specifications

CAS Number

[24305-27-9]

Product Name Alternative

Thyrotropin-releasing-hormone; TRH

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Thyroid Hormone Receptor

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Protirelin.html

Purity

99.98

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC3)NC3=O)=O)=O)CCC1

Molecular Formula

C16H22N6O4

Molecular Weight

362.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Van Sinay E, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114 (20) :E4065-E4074.|[2]Noda Y, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, Protirelin) in the rat. Kurume Med J. 1979;26 (2) :107-12.