ABBV-3373
Product Specifications
UNSPSC Description
ABBV-3373 is an anti-TNF antibody drug conjugate (ADC). ABBV-3373 is composed of the humanized antibody Adalimumab (HY-P9908) conjugated with a glucocorticoid receptor modulator (HY-148436). ABBV-3373 can be used in the study of rheumatoid arthritis[1].
Target Antigen
Antibody-Drug Conjugates (ADCs); Glucocorticoid Receptor; TNF Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related;Apoptosis;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/abbv-3373.html
Smiles
[ABBV-3373]
References & Citations
[1]Qu P, et al. Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate. J Med Chem. 2022 Dec 8;65(23):15893-15934.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164894/ABBV-3373-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164894/
Clinical Information
Phase 2
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