SERTlight
Product Specifications
UNSPSC Description
SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sertlight.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(C=C(F)C(OC(C(F)(F)F)=O)=C2)C=C1CCN
Molecular Weight
318.22
References & Citations
[1]Lee WL, et al. Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. J Am Chem Soc. 2024;146(14):9564-9574.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D2335/SERTlight-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D2335/
Clinical Information
No Development Reported
Curated Selection
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