HN37
Product Specifications
UNSPSC Description
HN37 as a potent and chemically stable antiepileptic agent candidate, with an EC50 of 37 nM for KCNQ2[1]. HN37 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hn37.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(CN(CC#C)C2=CC(C)=C(NC(OC)=O)C(C)=C2)C=C1
Molecular Weight
340.39
References & Citations
[1]Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145016/HN37-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145016/HN37-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1821222-10-9
Available Sizes
Curated Selection
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