Anticancer agent 126
Anticancer agent 126 (compound 12) is a WDR5 inhibitor with anticancer effects. Anticancer agent 126 disrupts WDR5-MYC interaction in cells and reduce MYC target gene expression[1].
Product Specifications
CAS Number
[3033748-20-5]
UNSPSC
12352005
Target
WDR5
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-126.html
Purity
98.0
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=C(C(F)=CC(C2=CC(S(=O)(F)=O)=CC=C2)=C1)CNC(C3=NN(C(C)=CC3=O)C4=CC=CC=C4)=O
Molecular Formula
C25H18F3N3O4S
Molecular Weight
513.49
References & Citations
[1]Jian Ding, et al. Discovery and Structure-Based Design of Inhibitors of the WD Repeat-Containing Protein 5 (WDR5) -MYC Interaction. J Med Chem. 2023 Jun 22;66 (12) :8310-8323.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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