Ac-Exatecan-d5
Ac-Exatecan-d5 is the deuterium labeled Ac-Exatecan (HY-79490) [1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Isotope-Labeled Compounds; Topoisomerase
Type
Isotope-Labeled Compounds
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others
Field of Research
Others
Purity
99.93
Solubility
10 mM in DMSO
Smiles
O=C1OCC(C(N2C(C3=NC4=CC(F)=C(C5=C4C([C@H](CC5)NC(C)=O)=C3C2)C)=C6)=O)=C6[C@]1(C([2H])(C([2H])([2H])[2H])[2H])O
Molecular Formula
C26H19D5FN3O5
Molecular Weight
482.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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