Decyclohexanamine-Exatecan
Decyclohexanamine-Exatecan (compound a) is a Camptothecin derivative, with a structure containing Exatecan (HY-13631), which can be used as a ADC cytotoxin[1].
Product Specifications
CAS Number
[2505045-51-0]
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/decyclohexanamine-exatecan.html
Purity
98.92
Solubility
DMSO : ≥ 32 mg/mL
Smiles
CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5C)=C2)=O)O
Molecular Formula
C21H17FN2O4
Molecular Weight
380.37
References & Citations
[1]Ravi Chari, et al. Camptothecin derivatives. Patent WO2020219287 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Curated Selection
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