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Fedovapagon

Fedovapagon (VA106483) is a selective and orally active vasopressin V2 receptor (V2R) agonist with an EC50 of 24 nM. Fedovapagon can be used in the research of nocturia[1].

Product Specifications

CAS Number

[347887-36-9]

Product Name Alternative

VA106483

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Vasopressin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fedovapagon.html

Purity

99.43

Solubility

DMSO : ≥ 125 mg/mL

Smiles

CC1=C(CNC(N2CCC[C@]2(C(N(C)C)=O)[H])=O)C=CC(C(N3CCCCC4=C3C=CC=C4)=O)=C1

Molecular Formula

C27H34N4O3

Molecular Weight

462.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Yea CM, et al. New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med Chem. 2008 Dec 25;51 (24) :8124-34.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

V2 Receptor

Available Sizes

Curated Selection

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