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Rilonacept

Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes[1].

Product Specifications

CAS Number

[501081-76-1]

Product Name Alternative

Arcalyst; IL 1 Trap; Interleukin 1 Trap

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rilonacept.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

[Rilonacept]

Molecular Weight

(201.243 kDa)

References & Citations

[1]Kapur S, et, al. Rilonacept (arcalyst), an interleukin-1 trap for the treatment of cryopyrin-associated periodic syndromes. P T. 2009 Mar;34 (3) :138-41.

Shipping Conditions

Isolate blue ice and the product with bubble pack to avoid direct contact

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

Launched

Isoform

IL-1

Available Sizes

Curated Selection

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