OXFBD02
OXF BD 02 is a selective inhibitor of BRD4 (1) (the first bromodomain of BRD4) with IC50 value of 382 nM[1].
Product Specifications
CAS Number
[1429129-68-9]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxfbd02.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1)C2=CC(O)=CC(C3=C(C)ON=C3C)=C2
Molecular Formula
C18H17NO3
Molecular Weight
295.33
References & Citations
[1]Hewings DS, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J Med Chem. 2013 Apr 25;56 (8) :3217-27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Available Sizes
Curated Selection
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