DBCO-amine
DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-amine is used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1255942-06-3]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
ADC Related
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-amine.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCN
Molecular Formula
C18H16N2O
Molecular Weight
276.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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