YL-939

YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis[1].

Product Specifications

CAS Number

[3023925-68-7]

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/yl-939.html

Concentration

10mM

Purity

99.03

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C1(C2=CN3C=C(N=C(C3=N2)C4=CCOCC4)C5=CN(N=C5)C6CCNCC6)=CC=CC=C1

Molecular Formula

C25H26N6O

Molecular Weight

426.51

References & Citations

[1]Yang W, et, al. Non-classical ferroptosis inhibition by a small molecule targeting PHB2. Nat Commun. 2022 Dec 3;13 (1) :7473.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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