Monobutyl phthalate-d4

Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate[1]. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[2][3].

Product Specifications

CAS Number

[478954-81-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Endocrinology

Purity

99.33

Solubility

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

Smiles

CCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O

Molecular Formula

C12H10D4O4

Molecular Weight

226.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]van Dartel DA, et al. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod Toxicol. 2009 Apr;27 (2) :93-102.|[3]Ema M, et al. Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats. Congenit Anom (Kyoto) . 2002 Dec;42 (4) :297-308.