Tegoprubart

Tegoprubart is a monoclonal antibody directed against CD40 ligand (CD40L), a key mediator of costimulation. Inhibition of CD40L reduces cellular and antibody-mediated immunity and creates a more tolerant immune environment. Tegoprubart was demonstrated to have in vivo efficacy in transplantation animal models.

Product Specifications

CAS Number

[2628092-47-5]

Product Name Alternative

AT-1501

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tegoprubart.html

Purity

99.90

Solubility

10 mM in DMSO

Smiles

[Tegoprubart]

Molecular Weight

(145.56 kDa)

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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