Cortodoxone
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation[1][2].
Product Specifications
CAS Number
[152-58-9]
Product Name Alternative
11-Deoxycortisol; cortexolone; Reichstein's substance S
UNSPSC
12352211
Hazard Statement
H410
Target
Endogenous Metabolite; Glucocorticoid Receptor
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Cortodoxone.html
Purity
98.74
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
Molecular Formula
C21H30O4
Molecular Weight
346.47
Precautions
H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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