Anti-CD25 [2E4]
Product Specifications
Gene Name
[CD25]
NCBI Gene ID
16184
Reactivity
Mouse
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
2E4 recognizes mouse CD25. This epitope is distinct from the IL-2 binding site and does not block binding of IL-2 to CD25. This antibody binds the same or overlapping epitope as 7D4 (Ab02216) but different than Ab01107. Murine CD25 is a 55 kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor.
Other Gene Names
[Il2ra; Il2ra; CD25; Il2r; Ly-43; Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA]
Short Name
[CD25]
Other Product Names
[Interleukin-2 receptor subunit alpha; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; IL2-RA; IL-2-RA; p55 chain; IL-2R alpha chain; IL-2R subunit alpha; IL-2 receptor subunit alpha; interleukin 2 receptor, alpha chain; p55; CD_antigen: CD25]
NCBI GI Number
124318
NCBI Accession Number
P01590.1
Uniprot Accession Number
P01590
CAS Number
9007-83-4
Available Sizes
Curated Selection
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