Benoxaprofen

Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen is a relatively weak inhibitor of cyclooxygenase in in vitro systems, inhibits lipoxygenase in other systems, and inhibits monocyte migration in some animal models of inflammation[1][2].

Product Specifications

CAS Number

[51234-28-7]

Product Name Alternative

LRCL 3794

UNSPSC

12352005

Hazard Statement

H301, H413

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/benoxaprofen.html

Purity

99.24

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)C1=CC=C(OC(C2=CC=C(Cl)C=C2)=N3)C3=C1

Molecular Formula

C16H12ClNO3

Molecular Weight

301.72

Precautions

H301, H413

References & Citations

[1]Cashin CH, et al. The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis. J Pharm Pharmacol. 1977;29 (6) :330-336.