HDAC6-IN-23
HDAC6-IN-23 (compound 9) is an orally active HDAC6 inhibitor[1].
Product Specifications
CAS Number
[2991427-09-7]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-23.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)C(O1)=NN=C1C(C=N2)=CC=C2CN3N=NC(C4=NC=CC=C4)=N3
Molecular Formula
C15H10F2N8O
Molecular Weight
356.29
References & Citations
[1]Ripa L, et al. Selective and Bioavailable HDAC6 2- (Difluoromethyl) -1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism [published online ahead of print, 2023 Oct 5]. J Med Chem. 2023;10.1021/acs.jmedchem.3c01269.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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