RABBIT ANTI HUMAN CD261 (N-TERMINAL)

Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.<br>Shelf Life: 18 months from date of despatch.

This item recognises the 57kD apoptosis related protein designated DR-4 (death receptor 4), also known as CD261.DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.

[tumor necrosis factor receptor superfamily member 10A; Tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10A; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; cytotoxic TRAIL receptor; death receptor 4; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD_antigen: CD261]