CDK9-IN-10
CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811) [1].
Product Specifications
CAS Number
[3542-63-0]
UNSPSC
12352005
Target
CDK; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-10.html
Purity
98.09
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC1=C2C(C(C=C(C3=CC=CC=C3)O2)=O)=C(O)C=C1OCC4=CC=CC=C4
Molecular Formula
C22H16O5
Molecular Weight
360.36
References & Citations
[1]Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
Available Sizes
Curated Selection
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