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CDK9-IN-10

Product Specifications

UNSPSC Description

CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1].

Target Antigen

CDK; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-10.html

Purity

98.00

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OC1=C2C(C(C=C(C3=CC=CC=C3)O2)=O)=C(O)C=C1OCC4=CC=CC=C4

Molecular Weight

360.36

References & Citations

[1]Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130850/CDK9-IN-10-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130850/CDK9-IN-10-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

3542-63-0

Available Sizes

Curated Selection

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