AMPK-IN-4
AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK (α1) and AMPK (α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1].
Product Specifications
CAS Number
[873077-70-4]
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ampk-in-4.html
Purity
97.16
Solubility
DMSO : 20 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl)
Smiles
O=C(/C(C1=C2)=C\C3=C(C(C(NCCN)=O)=C(N3)C)C)NC1=CC=C2F
Molecular Formula
C18H19FN4O2
Molecular Weight
342.37
References & Citations
[1]Christopher J Matheson, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1:197:112316.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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