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AMPK-IN-4

AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK (α1) and AMPK (α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1].

Product Specifications

CAS Number

[873077-70-4]

UNSPSC

12352005

Target

AMPK

Type

Reference compound

Related Pathways

Epigenetics; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ampk-in-4.html

Purity

97.16

Solubility

DMSO : 20 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl)

Smiles

O=C(/C(C1=C2)=C\C3=C(C(C(NCCN)=O)=C(N3)C)C)NC1=CC=C2F

Molecular Formula

C18H19FN4O2

Molecular Weight

342.37

References & Citations

[1]Christopher J Matheson, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1:197:112316.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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