Cyclopentolate

Cyclopentolate (DL-Cyclopentolate) is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle) . Cyclopentolate is an anti-muscarinic agent commonly used in the ophthalmologic practice[1][2].

Product Specifications

CAS Number

[512-15-2]

Product Name Alternative

DL-Cyclopentolate

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cyclopentolate.html

Solubility

10 mM in DMSO

Smiles

CN(CCOC(C(C1(CCCC1)O)C2=CC=CC=C2)=O)C

Molecular Formula

C17H25NO3

Molecular Weight

291.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.|[2]Ishikawa H, DeSantis L, Patil PN. Selectivity of muscarinic agonists including (+/-) -aceclidine and antimuscarinics on the human intraocular muscles. J Ocul Pharmacol Ther. 1998;14 (4) :363‐373.|[3]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.