(2R,3S)-Azelaprag
Product Specifications
UNSPSC Description
(2R,3S)-Azelaprag ((2R,3S)-AMG 986) is an Apelin receptor agonist with an EC50 of 0.012 µM for Apelin receptors, and it is utilized in the treatment of various conditions such as heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke, and myocardial infarction.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2r-3s-azelaprag.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=S(NC1=NN=C(C2=CN=CC(C)=C2)N1C(C(OC)=CC=C3)=C3OC)([C@H](C)[C@H](C4=NC=C(C)C=N4)C)=O
Molecular Weight
523.61
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-167712/2R-3S-Azelaprag-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-167712/2R-3S-Azelaprag-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2049979-31-7
Available Sizes
Curated Selection
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