5-Androstenetriol
Product Specifications
UNSPSC Description
5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of hydrocortisone (HY-N0583)[1][2].
Target Antigen
Endogenous Metabolite; IFNAR; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-androstenetriol.html
Smiles
C[C@@]12[C@@H](O)[C@H](O)C[C@@]1([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2
Molecular Weight
306.44
References & Citations
[1]R M Loria, et al. Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injury. Ann N Y Acad Sci. 2000:917:860-7.|[2]Mark H Whitnall, et al. Molecular specificity of 5-androstenediol as a systemic radioprotectant in mice. Immunopharmacol Immunotoxicol. 2005;27(1):15-32.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113271/5-Androstenetriol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113271/
Clinical Information
Phase 4
CAS Number
4150-30-5
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