Kaempferitrin

Kaempferitrin is a natural flavonoid, possesses antinociceptive, anti-inflammatory, anti-diabetic, antitumoral and chemopreventive effects, and activates insulin signaling pathway.

Product Specifications

CAS Number

[482-38-2]

Product Name Alternative

Lespedin; Lespenephryl

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Insulin Receptor

Type

Natural Products

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Kaempferitrin.html

Purity

99.81

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C(O[C@H](O[C@@H](C)[C@H](O)[C@H]2O)[C@@H]2O)=C(C3=CC=C(O)C=C3)OC4=CC(O[C@H](O[C@@H](C)[C@H](O)[C@H]5O)[C@@H]5O)=CC(O)=C14

Molecular Formula

C27H30O14

Molecular Weight

578.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Tzeng YM, et al. Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes. Eur J Pharmacol. 2009 Apr 1;607 (1-3) :27-34.|[2]Alonso-Castro AJ, et al. Kaempferitrin induces apoptosis via intrinsic pathway in HeLa cells and exerts antitumor effects. J Ethnopharmacol. 2013 Jan 30;145 (2) :476-89.