Pavinetant
Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.
Product Specifications
CAS Number
[941690-55-7]
Product Name Alternative
MLE-4901; AZD2624; AZD4901
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MLE-4901.html
Purity
99.83
Solubility
DMSO : ≥ 50 mg/mL
Smiles
CC[C@H](NC(C1=C(C=CC=C2)C2=NC(C3=CC=CC=C3)=C1NS(C)(=O)=O)=O)C4=CC=CC=C4
Molecular Formula
C26H25N3O3S
Molecular Weight
459.56
References & Citations
[1]Li Y, et al. In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P (450) enzyme identification, inhibition, and induction studies. Xenobiotica. 2010 Nov;40 (11) :721-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
NK3R
Available Sizes
Curated Selection
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