Biotinylated Human Claudin-18.2 Protein (VLP)
Biotinylated Human Claudin-18.2 Protein (VLP) (CL2-H82P3) is expressed from human 293 cells (HEK293) . It contains AA Lys 25 - Asp 184 (Accession # P56856-2) .
Product Specifications
Background
Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.
Specifications
This protein .
Accession Number
P56856-2
Expression Region
Lys 25 - Asp 184
Host
HEK293
Target
Claudin-18.2
Conjugation
Biotin-labeled
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CL2-H82P3.pdf
Species
Human
Curated Selection
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