Human 5-HT2AR Full Length Protein, Flag, His Tag (Nanodisc-pro)
Human 5-HT2AR Full Length Protein, Flag, His Tag (5HR-H55D4) is expressed from Baculovirus-Insect cells. It contains AA Asp 2 - Lys 403 (Accession # P28223-1) .
Product Specifications
Background
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD) . MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.
Accession Number
P28223-1
Expression Region
Asp 2 - Lys 403
Host
Insect Cells
Target
5-HT2AR
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
20 mM HEPES, 150 mM NaCl, pH7.5
Additives
Glycerol
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
500ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/5HR-H55D4.pdf
Species
Human
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