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APC-Labeled CD3 epsilon&CD3 gamma Heterodimer Protein, Fc, His Tag&Fc, Flag Tag

APC-Labeled CD3E & CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDG-HA2W3) is expressed from human 293 cells (HEK293) . It contains AA Asp 23 - Asp 126 & Gln 23 - Ser 116 (Accession # P07766-1 & P09693-1) .

Product Specifications

Background

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Specifications

APC-Labeled CD3E & CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G) . The subunit CD3E carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The subunit CD3G carries a human IgG1 Fc fragment at the C-terminus, followed by a flag tag.

Accession Number

P07766-1 & P09693-1

Expression Region

Asp 23 - Asp 126 & Gln 23 - Ser 116

Host

HEK293

Target

CD3E & CD3G

Conjugation

APC Labeled

Tag

C-Fc & C-6xHis | C-Fc & C-Flag

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

39.2 kDa & 38.6 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

200ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/CDG-HA2W3.pdf

Species

Human

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