APC-Labeled CD3 epsilon&CD3 gamma Heterodimer Protein, Fc, His Tag&Fc, Flag Tag
APC-Labeled CD3E & CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDG-HA2W3) is expressed from human 293 cells (HEK293) . It contains AA Asp 23 - Asp 126 & Gln 23 - Ser 116 (Accession # P07766-1 & P09693-1) .
Product Specifications
Background
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Specifications
APC-Labeled CD3E & CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G) . The subunit CD3E carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The subunit CD3G carries a human IgG1 Fc fragment at the C-terminus, followed by a flag tag.
Accession Number
P07766-1 & P09693-1
Expression Region
Asp 23 - Asp 126 & Gln 23 - Ser 116
Host
HEK293
Target
CD3E & CD3G
Conjugation
APC Labeled
Tag
C-Fc & C-6xHis | C-Fc & C-Flag
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
39.2 kDa & 38.6 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CDG-HA2W3.pdf
Species
Human
Curated Selection
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