GYPB Polyclonal Antibody
This is a GYPB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.
Synonyms
GYPB, CD235b, GPB, GYP, MNS, PAS-3, SS
Gene ID
2994
Swiss Prot
P06028
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human GYPB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
85kDa/90kDa
Observed Molecular Weight
75KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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