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PAFAH1B1 Polyclonal Antibody

This is a PAFAH1B1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) . Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Synonyms

PAFAH1B1, LIS1, LIS2, MDCR, MDS, NudF, PAFAH

Gene ID

5048

Swiss Prot

P43034

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human PAFAH1B1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

11kDa

Observed Molecular Weight

11-15kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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