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OCT4 Polyclonal Antibody

This is a 45934 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Synonyms

POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4

Gene ID

5460

Swiss Prot

Q01860

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human OCT4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

46kDa/48kDa

Observed Molecular Weight

47kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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