FADD Polyclonal Antibody
This is a FADD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95 or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Synonyms
Mort1/F, Mort1/FADD
Gene ID
14082
Swiss Prot
Q61160
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of mouse FADD
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:200-1:2000, IF 1:50-1:200, IP 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
46-75KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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