Ap4dT
Product Specifications
UNSPSC Description
Ap4dT is an inhibitor for human adenylate kinase isozyme 1 (hAK1), that inhibits the ATP and ADP synthesis with IC50s of 42 μM and 38 μM[1].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ap4dt.html
Smiles
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(OP(OP(OC[C@H]4O[C@@H](N5C=C(C)C(NC5=O)=O)C[C@@H]4O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O.[NH4+].[NH4+].[NH4+].[NH4+]
Molecular Weight
879.50
References & Citations
[1]Kozakiewicz-Piekarz A, et al., Synthesis, kinetic studies, and QSAR of dinucleoside polyphosphate derivatives as human AK1 inhibitors. Bioorg Chem. 2024 Jul;148:107432.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168345/Ap4dT-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168345/
Clinical Information
No Development Reported
CAS Number
1146545-74-5
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