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(KO Validated) POR Polyclonal Antibody

This is a (KO Validated) POR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Synonyms

POR, CPR, CYPOR, P450R

Gene ID

5447

Swiss Prot

P16435

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human POR (NP_000932.3) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

76 kDa

Observed Molecular Weight

77 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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