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C12orf5 Polyclonal Antibody

This is a C12orf5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

Synonyms

6-bisphosphatase TIGAR, C12ORF5, chromosome 12 open reading frame 5, FR2BP, Fructose-2,6-bisphosphatase TIGAR, Fructose-2,6-bisphosphate 2-phosphatase, Probable fructose 2,6 bisphosphatase TIGAR, Probable fructose-2, tigar, TIGAR, TP53 induced glycolysis and apopto

Swiss Prot

Q9NQ88

Accession Number

NP_065108

Reactivity

Human

Immunogen

Synthetic peptide of human C12orf5

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.4 mg/mL

Dilution

IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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