SLC22A17 Polyclonal Antibody
This is a SLC22A17 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Synonyms
24p3 receptor,24p3R, BOCT, BOIT, Brain type organic cation transporter, Brain-type organic cation transporter, hBOIT, Lipocalin-2 receptor, Neutrophil gelatinase associated lipocalin receptor, Neutrophil gelatinase-associated lipocalin receptor, NGAL receptor, Ngal
Swiss Prot
Q8WUG5
Accession Number
NP_065105.2
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SLC22A17
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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