LRP5 Polyclonal Antibody
This is a LRP5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Synonyms
BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2
Swiss Prot
O75197
Accession Number
NP_002326
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human LRP5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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