Denecimig

Denecimig (Mim8) is a novel activated coagulation factor VIII-mimetic human bispecific antibody with anti-FIXa and anti-FX arms that potently stimulates FX activation resulting in efficacious haemostasis in vitro and in vivo[1].

Product Specifications

CAS Number

[2488745-86-2]

Product Name Alternative

Mim8

UNSPSC

12352203

Target

Factor Xa

Type

Inhibitory Antibodies

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/denecimig.html

Purity

95.90

Solubility

10 mM in DMSO

Smiles

[Denecimig]

Molecular Weight

(145.46 kDa)

References & Citations

[1]Stine L Kjellev, et al. Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo