AADAC Polyclonal Antibody
This is a AADAC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Synonyms
AAAD, Aada, Aadac, Arylacetamide deacetylase (esterase), Arylacetamide deacetylase, CES5A1, DAC
Swiss Prot
P22760
Accession Number
BC032309
Reactivity
Human
Immunogen
Recombinant protein of human AADAC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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