PRMT7 Polyclonal Antibody
This is a PRMT7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT) .
Synonyms
[Myelin basic protein]-arginine N-methyltransferase PRMT7, ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine methyltransferase 7, Protein arginine N-
Swiss Prot
Q9NVM4
Accession Number
BC000146
Reactivity
Human
Immunogen
Recombinant protein of human PRMT7
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
78 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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