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HDAC5 Polyclonal Antibody

This is a HDAC5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

Synonyms

Antigen NY CO 9, Antigen NY-CO-9, HD5, HDAC 5, HDAC5, HDAC5, Histone deacetylase 5, NY CO 9

Swiss Prot

Q9UQL6

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of Ser498.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC-p, IF, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

122 kDa

Observed Molecular Weight

122 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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