Cleaved-PARP1 (D214) Polyclonal Antibody
This is a Cleaved-PARP1 (D214) Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Synonyms
ADP-ribosyltransferase diphtheria toxin-like 1, ADPRT 1, ADPRT, ADPRT1, APOPAIN, ARTD1, NAD (+) ADP-ribosyltransferase 1, PARP, PARP-1, PARP1, PARP1, Poly [ADP-ribose] polymerase 1, Poly ADP ribose polymerase 1, Poly[ADP-ribose] synthase 1, PPOL, SCA1
Swiss Prot
P09874
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human PARP-1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
113 kDa
Observed Molecular Weight
24 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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