EIF2AK3 Polyclonal Antibody
This is a EIF2AK3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Synonyms
EIF2AK3, PEK, PERK, WRS
Gene ID
9451
Swiss Prot
Q9NZJ5
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human EIF2AK3
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
125 kDa
Observed Molecular Weight
160 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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