Icam5 Polyclonal Antibody
This is a Icam5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.
Synonyms
ICAM5, TLCN, TLN, Icam5
Gene ID
15898
Swiss Prot
Q60625
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of mouse Icam5 (NP_032345.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
96 kDa
Observed Molecular Weight
140 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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