Rb Polyclonal Antibody
This is a Rb Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Synonyms
OSRC, PPP1R130, RB, p105-Rb, pRb, pp110, RB1, Rb
Gene ID
5925
Swiss Prot
P06400
Reactivity
Human
Immunogen
Recombinant fusion protein of human Rb (NP_000312.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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